Specification: 

12 tests /kit

Applicable instrument:

Stratagene Mx3000P、ABI 7500、Roche LC480、Abbott m2000rt、BioRad CFX-96

Product Description:

Adopting the ARMS-PCR method, this kit can be used to detect 7 hot-spot mutations in codons 12 and 13 of exon 2 of the KRAS gene, about more than 95% of known mutation loci in clinical research.    

This kit is used for qualitative assay of mutations in the KRAS gene of human patients with non-small cell lung cancer (NSCLC) and colorectal cancer. The product contains our proprietary stabilizer with which high specificity can be guaranteed and false positives can be avoided under the situation when the sensitivity reaches 1%. The assay result can be used as the reference for clinicians’ selection of population who may receive anti-EGFRs (targeted drugs) among patients with NSCLC and colorectal cancer. The product can be used in in vitro tests only.  

Product Features:

High selectivity——Detect as low as 1% of mutations in 5 ng/μl DNA from multiple types of samples

High sensitivity——Only a few hundred copies are needed to detect the target gene

High specificity——The amplification curve is flattening when wild type samples are tested

Easy to operate—— Pre-assembled to facilitate standard operation in the lab

Convenient and fast——Suitable for various PCR instruments, test completed in 90 minutes 

Stable and reliable——Closed tube reaction, IR-IC dual QC to avoid false negatives and positives

Convenient read-out——No non-specific amplification, read the result directly, no need to manually calculate the △CT value

Worry-free after-sales service——Instant response, comprehensive after-sales service   

Product Qualification:

This kit meets the requirements of the ISO13485 Quality Management System and passed CE certification.